Best Online Semaglutide Programs in 2026 (8 Providers Compared)

Which online semaglutide program fits you?

• Lowest price without prepaying: Eden, about $100 a month at every dose, all in.
• If you can prepay a year: BetterMe Rx, about $100 a month on its 12-month plan. Nothing is refunded once an order is processed.
• FDA-approved drug without insurance: Wegovy direct from Novo Nordisk, from about $150 a month for the pill.
• One bill, no membership: Henry Meds, from about $250 a month for the tablet or about $300 for the shot.
• Shot, pill or microdose: Mochi Health, from about $140 a month. The price rises with your dose.
• LegitScript-certified flat rate: Willow, about $300 a month, in 36 states.
• Brand Wegovy with a care platform: Hers, at Novo's cash prices plus a monthly membership.
• Insurance that might cover Wegovy: WeightWatchers Med+, which helps with approvals. Its membership is billed apart from the medicine.

Best compounded semaglutide online: Mochi Health

Mochi Health is our top pick for its range: a shot, a pill or a microdose, from one care team. Mochi prices the medicine by dose. It costs $60 a month at the starter dose. At the top dose, it costs about $190.

The only add-on is a monthly membership of about $80. It covers provider visits, messaging and care coordination. New members currently get the first month of membership free, so month one at the starter dose costs $60. The free month is not offered in every state. After that, expect about $140 a month at first, rising to about $270 at the top dose.

Mochi also offers more choice than most: a weekly shot, a weekly pill and a microdosing plan. Its doctors include specialists board-certified in obesity medicine, which is rare even in specialty clinics. Mochi serves all 50 states.

Two things to know before you enroll. The medicine and membership are billed separately, and that setup has drawn billing complaints, so read the cancellation terms. Also, Washington State shut down Mochi's former main pharmacy, Aequita, in March 2025. Ask in writing which pharmacy fills your prescription now.

• Pros: low starting price without prepaying; shot, pill or microdosing; obesity-medicine specialists; all 50 states; shipping included.
• Cons: the price rises with your dose; the membership is a separate charge; the two-part billing has drawn BBB complaints; confirm the current pharmacy.

Other compounded semaglutide programs worth comparing

BetterMe Rx: a low price if you can pay for a year

BetterMe Rx's best semaglutide rate needs its 12-month plan. That plan works out to about $100 a month. You pay it as one charge of about $1,190.

Shorter plans cost more. The price stays the same at every dose, with no membership. Visits and shipping are included. Its FAQ names its doctor networks and seven US pharmacies.

• 12 months: about $100 a month, paid upfront.
• 6 months: about $140 a month.
• 3 months: about $160 a month.
• Month to month: about $200.

It isn't our top pick because of its track record. Once an order is processed, nothing is refunded, including unused months of a prepaid plan. Reviews are mixed, with complaints about leaking vials and slow support. The site doesn't publish the company's legal name. If you're new to semaglutide, consider the 3-month plan first.

Henry Meds: bundled, no membership, tablet or shot

Henry Meds is one of the most established names in compounded GLP-1 telehealth. One price covers the medicine, provider visits, supplies and shipping, with no separate membership.

The shot costs about $300 a month, month to month. Prepaying lowers it to about $245 a month for 6 months, or about $200 a month for 12 months. The tablet costs about $250 a month. Henry doesn't promise one price at every dose, so ask what your maintenance dose will cost.

The tablet suits women who'd rather not inject. Keep in mind that compounded tablets have far less evidence behind them than the shots or the FDA-approved Wegovy pill. Henry serves about 40 states plus DC.

• Pros: truly all-in pricing with no membership; tablet or shot; large, established platform; about 40 states plus DC.
• Cons: at about $300 a month, the shot costs more than Mochi at its top dose. The cheapest rate needs a 12-month prepay before you know how you respond.

Eden: the lowest price without prepaying

Eden charges about $100 a month, all in, at every dose. There is no membership, no prepay and no intro price that jumps later.

That makes Eden the cheapest way here to try compounded semaglutide month to month. Weigh the price against its record, covered in our Eden review.

• Pros: lowest price here without prepaying; same price at every dose; month to month.
• Cons: a June 2026 FDA warning letter over its marketing; a BBB rating of F, with a flagged pattern of billing complaints. Ask which pharmacy fills your order.

Hers: brand-name Wegovy now, compounded only by exception

Hers, the women's health arm of Hims & Hers, used to lead with compounded semaglutide. After a March 2026 agreement with Novo Nordisk, it now offers brand-name, FDA-approved Wegovy instead.

The medicine costs the same as buying direct from Novo. The pill runs about $150 to $300 a month by dose. The pen costs about $200 for the first two fills, then about $350. A separate membership of about $150 a month comes on top. Its first month costs $39. Compounded semaglutide no longer appears on the Hers storefront.

If compounded pricing is why you're looking at Hers, another program here fits better. If you want brand Wegovy with coaching, compare Hers with buying direct from Novo, which costs the same without the membership.

• Pros: FDA-approved Wegovy pill and pen at Novo's cash prices; familiar women's telehealth platform; clinician messaging and nutrition guidance.
• Cons: the membership is billed apart from the medicine and doesn't cancel with it; compounded semaglutide is no longer offered.

Willow: flat rate, LegitScript certified, 36 states

Willow charges about $300 a month for compounded semaglutide, as a shot or a tablet. The price includes the medicine, physician access and free two-day shipping. There is no membership. The price stays the same at every dose up to 3.5 mg.

Willow is LegitScript certified, a third-party check of online pharmacies and clinics that few telehealth programs hold. It publishes a US address in Texas and names its partner pharmacies. The main limit is geography, since Willow serves 36 states.

• Pros: LegitScript certified; same price at every dose; no membership; free two-day shipping; shot or tablet.
• Cons: only 36 states; about $300 is more than Mochi at its top dose and more than Henry's tablet.

WeightWatchers Med+: best if insurance is your path

WeightWatchers bought Sequence to help members get insurance to cover brand-name GLP-1s. Its Med+ membership costs about $75 a month on a 12-month plan, or about $85 on a 6-month plan. The first month costs $25 on either plan. The membership covers clinician visits, insurance help and WW's coaching program.

The medicine is billed separately and depends on your plan. If your commercial insurance might cover Wegovy, Med+ can help get it approved. If you pay cash, the membership on top of the medicine makes other programs cheaper.

• Pros: strong insurance help; prescribes brand-name, FDA-approved Wegovy; WW coaching included.
• Cons: the membership comes on top of the medicine; you commit to 6 or 12 months; a poor fit if you have no usable insurance.

Brand-name Wegovy: the FDA-approved alternative

Every compounded program here sells a pharmacy-mixed version of semaglutide, not the FDA-approved drug. Wegovy, as a weekly pen or a daily pill, is the regulated product. Novo Nordisk makes it to consistent standards, with FDA-reviewed safety data.

Brand-name Wegovy is no longer out of reach without insurance. Bought direct through NovoCare, Novo's own pharmacy, the pill starts at about $150 a month. Higher doses cost up to about $300 a month.

New NovoCare patients pay about $200 a month for their first two pen fills. That offer runs through December 31, 2026.

• Wegovy pill: about $150 a month at the starting dose · about $200 at the next dose · about $300 at the two highest doses.
• Wegovy pen: about $200 for each of the first two fills · then about $350 a month.
• Wegovy HD pen, the 7.2 mg high dose: about $400 a month.

With insurance, it can cost even less. Wegovy is approved for adults with a BMI of 30 or higher, or 27 with a weight-related health condition. Many commercial plans that cover it use those limits. If yours does, Novo's savings card can bring your cost down to as little as $25 a month. The card saves you at most $100 a month, so a high copay can leave you paying more.

On Medicare? Since July 1, 2026, the Medicare GLP-1 Bridge prices Wegovy, pen or pill, at $50 a month for eligible Part D and Medicare Advantage members. It runs through December 31, 2027. Check your own coverage before you default to compounded.

• FDA status: Wegovy is FDA-approved. Compounded semaglutide is not, and its manufacturing review is different.
• Watch the wording: a provider calling compounded semaglutide "generic Wegovy" or an "FDA-approved compound" is misstating it.
• Wegovy pill: a daily tablet approved in December 2025. It is brand-name only, and no compounded tablet is FDA-approved.

Is compounded semaglutide still legal in 2026?

Yes, through 503A pharmacies, but the rules have narrowed since 2025. The FDA declared the semaglutide shortage over on February 21, 2025. That ended the main exception that let 503B outsourcing facilities, which are larger federally registered compounders, make it in bulk.

On April 30, 2026, the FDA proposed formally excluding semaglutide, tirzepatide and liraglutide from 503B bulk compounding. The comment period closed July 30, 2026. As of October 2, 2026, the FDA had not made a final decision.

What remains legal is 503A compounding. A state-licensed pharmacy makes the medicine for one named patient, under a valid prescription with a medical reason.

Rules could still change, and supply could shift with them. Ask any provider which licensed pharmacy fills your prescription, and whether it is a 503A pharmacy. Also ask for a certificate of analysis, the lab report for your batch.

• Still legal: 503A compounding for individual patients with a valid prescription.
• Proposed ban: 503B bulk compounding of semaglutide, not final as of early October 2026.
• Safety reports: as of May 31, 2026, the FDA had received 990 reports of side effects or other harms tied to compounded semaglutide. Some may be linked to dosing errors.
• Before you start: get the pharmacy's name and a certificate of analysis.

Why semaglutide matters for women in perimenopause and menopause

Weight gain in perimenopause isn't simply about eating more or moving less. Falling estrogen shifts fat toward the belly and slows your metabolism. It also makes "eat less, move more" harder to stick to than it was at 30.

Semaglutide mimics GLP-1, a hormone your gut releases after eating. It slows digestion and quiets hunger, so eating less takes less willpower. In the STEP 1 trial, adults on weekly semaglutide lost about 15% of their body weight over 68 weeks, against about 2% on placebo.

It also has strong heart data. In the SELECT trial, adults with excess weight and existing heart disease had a 20% lower risk of major heart events. On semaglutide, 6.5% had one, against 8.0% on placebo.

Semaglutide isn't hormone therapy and doesn't treat hot flashes, poor sleep or vaginal symptoms. Some women pair it with hormone therapy. One small 2024 study in the journal Menopause found women using both lost more weight than women on semaglutide alone.

Price is rarely one number, so compare the ongoing all-in cost. Include the membership, any price rise with dose, the billing cycle and prepayment terms before you compare headline prices.