Online GLP-1 & HRT price index
What online weight-loss and menopause programs really charge each month, without insurance. We read each company's own price page and write down the same thing everywhere, so the numbers can be compared.
✓ 30 programs tracked · last price check Oct 11, 2026 · index of the week of Oct 5, 2026
Key findings
- Compounded tirzepatide costs about 36% more than compounded semaglutide: a median of $339 a month against $249.
- The same semaglutide injection costs $116 a month at the cheapest program and $299 at the most expensive. That gap is $2,196 over a year.
- At the starting dose, brand-name Zepbound bought direct from Lilly ($299) costs less than the typical compounded tirzepatide program ($339). From 7.5 mg, Zepbound costs $449.
- Online hormone therapy with estrogen and progesterone costs $63 to $199 a month without insurance, with a median of $163.
What each number means
Every price is the regular monthly price for a new patient at the starting dose. Required fees, such as a membership, are added in. First-month discounts, coupon codes and prepaid plans are left out, because they hide what you pay later.
The median is the middle price: half the programs charge more, half charge less. Only month-to-month prices checked in the last 45 days count toward it.
Compounded semaglutide: 21 monthly prices
Weekly injection, starting dose, from an online program. The median is $249 a month. Bliv is the cheapest at $116.
Advertised starting price; higher doses not published
Checked Sep 11, 2026
Month-to-month plan
Checked Oct 4, 2026
Per 28-day cycle, same price at every dose
Checked Oct 4, 2026
About $75 medicine + $74.99 required membership, starting dose
Checked Sep 13, 2026
Month-to-month plan, same price at every dose
Checked Oct 4, 2026
Every 4 weeks, after the first month
Checked Oct 4, 2026
Advertised "starting at" price
Checked Oct 4, 2026
Monthly plan, same price at every dose
Checked Oct 4, 2026
Regular monthly price, after the first-month promo
Checked Oct 4, 2026
Month-to-month plan, after the first-month code
Checked Oct 4, 2026
Month-to-month plan
Checked Oct 7, 2026
Month-to-month price, after the first month
Checked Oct 8, 2026
Listed, but not in the median
These programs sell no month-to-month plan, or their price is waiting for a new check.
12-month plan, the only price published
12-month plan · Checked Oct 4, 2026
Billed $537 per 3 months, after the first-month promo
3-month plan · Checked Oct 8, 2026
Compounded tirzepatide: 20 monthly prices
Weekly injection, starting dose, from an online program. The median is $339 a month. Mochi Health is the cheapest at $169.
Advertised starting price; higher doses not published
Checked Sep 11, 2026
About $125 medicine + $74.99 required membership, starting dose
Checked Sep 13, 2026
Month-to-month plan
Checked Oct 4, 2026
Month-to-month plan, same price at every dose
Checked Oct 4, 2026
Month-to-month plan
Checked Oct 7, 2026
Every 4 weeks, after the first month
Checked Oct 4, 2026
Monthly plan, same price at every dose
Checked Oct 4, 2026
Advertised "starting at" price
Checked Oct 4, 2026
Regular monthly price, after the first-month promo
Checked Oct 4, 2026
Month-to-month plan, after the first-month code
Checked Oct 4, 2026
Month-to-month price, after the first month
Checked Oct 8, 2026
Listed, but not in the median
These programs sell no month-to-month plan, or their price is waiting for a new check.
12-month plan, the only price published
12-month plan · Checked Oct 4, 2026
3-month plan, the shortest sold; all doses included
3-month plan · Checked Sep 10, 2026
Billed $747 per 3 months, after the first-month promo
3-month plan · Checked Oct 8, 2026
Online hormone therapy: 6 monthly prices
Estrogen plus progesterone, the cheapest combination each clinic sells. The median is $163 a month. Alloy is the cheapest at $63.
Estradiol pill $39.99 + progesterone $23; one-time $49 consult not included
Checked Sep 26, 2026
Estradiol pill from $26 + progesterone from $23 + $79 membership
Checked Oct 11, 2026
Compounded starter kit, billed monthly, shipped as a 3-month supply
Checked Oct 4, 2026
Listed, but not in the median
These programs sell no month-to-month plan, or their price is waiting for a new check.
Estradiol capsule $49 + progesterone $54 + $50 care plan, billed quarterly
3-month plan · Checked Oct 8, 2026
Brand-name prices, direct from the maker
For comparison, this is what the drug makers charge when you buy from their own pharmacy without insurance. You need a prescription. Checked Oct 10, 2026.
- Zepbound (tirzepatide), LillyDirect: $299 at 2.5 mg, $399 at 5 mg, $449 from 7.5 mg when each refill is ordered within 45 days.
- Wegovy pill (semaglutide), NovoCare Pharmacy: $149 at 1.5 mg, $199 at 4 mg, $299 at 9 and 25 mg.
- Wegovy pen (semaglutide), NovoCare Pharmacy: $349 a month, $399 for the 7.2 mg pen; first two fills $199 for new patients through Dec 31, 2026.
The index, week by week
We freeze the index every Monday. Tracking started in October 2026, so the series is short for now.
| Week of | Compounded semaglutide | Compounded tirzepatide | Online hormone therapy |
|---|---|---|---|
| Oct 5, 2026 | $249 (21) | $339 (20) | $163 (6) |
Median monthly price, with the number of programs counted.
How we collect the prices
- We read each price on the company's own website or checkout. We never copy another list.
- We date every check. Each program is checked again about once a month. A price older than 45 days leaves the median until we have checked it again.
- A program enters the index only if it publishes a price. Programs that quote after sign-up are left out.
- Prices are for the starting dose. Some programs charge more as the dose goes up. The note on each row says so.
- For hormone therapy we take the cheapest way to get estrogen plus progesterone at each clinic. The product can be a pill, a patch or a cream.
- Compounded drugs are mixed by a pharmacy. They are not approved by the FDA, and they are not the same product as Wegovy or Zepbound.
- Some of these companies pay us a commission when a reader signs up. It has no effect on this index: every program that publishes a price is listed, at the price we read. How we review.
Looking for help choosing, not raw numbers? See our ranked comparisons of GLP-1 programs and online hormone therapy.
Use this data
You are free to quote, chart or republish these numbers, as long as you link to this page (CC BY 4.0). The full table is available as a CSV file.
Source: MenoMellow Online GLP-1 & HRT Price Index, week of Oct 5, 2026. https://www.menomellow.com/price-index/
Journalist or researcher? Need a number we don't show, or want to report a price that changed? Write to contact@menomellow.com.