13 Cheapest GLP-1 Providers (2026)

Two different products: what you need to understand first

'GLP-1' covers a class of medications, not a single drug. The two most relevant in 2026 are semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro). Tirzepatide is a dual GIP/GLP-1 agonist — it works on two receptor types instead of one — and has shown greater average weight loss in head-to-head trials. Both are available as brand-name FDA-approved products and as compounded versions.

Compounded versions are made by 503A compounding pharmacies under individual-patient prescriptions. They are significantly cheaper than brand-name but are not FDA-approved as finished products. Both semaglutide and tirzepatide can be compounded legally under current rules, but the regulatory picture is actively evolving. This is the most important caveat in any GLP-1 price comparison right now.

The 13 cheapest GLP-1 programs, provider by provider

JoinSkinny — $149 per 28 days, flat at every semaglutide dose

JoinSkinny has the lowest flat rate on this page: $149 per 28-day cycle for compounded semaglutide, and that number does not move as your clinician titrates you up. Prescribing runs through the OpenLoop medical groups, the terms name the partner pharmacies, and the six-month weight-loss warranty is something almost no competitor puts in writing.

Register two things before you enroll. Billing is every 28 days, not monthly — thirteen charges a year, so the real annual cost is closer to $1,937 than "$149 × 12" suggests. And tirzepatide and oral prices only appear after the intake, so if you want the dual-agonist molecule this is not the cheapest verified route. Young brand, thin review history.

LevelsRx — from $150 semaglutide, from $240 tirzepatide, video visits included

LevelsRx is the newest name here and the one that puts a clinician on camera rather than behind a questionnaire: unlimited video visits, 1:1 nutrition coaching and shipping are bundled, and its partner pharmacies — including a known 503A compounder — are named in the terms. Semaglutide (injection or a daily oral liquid, same rate) is advertised from $150 a month and tirzepatide from $240. Treat both as floors: the real plan tiers only appear once you begin the intake, the discounted rate reportedly carries a three-month minimum, and there are only a handful of public reviews to go on.

Fridays — cheapest on an annual commitment

Fridays' annual plan brings compounded semaglutide to ~$150/mo — among the lowest prices available anywhere for a full-service program. The catch is commitment: month-to-month runs $249/mo, and the discount only applies if you pay for 12 months at once. The program includes dietitian access, lifestyle coaching, and app support bundled in.

• Pros: cheapest annual rate; dietitian and coaching included; no separate membership
• Cons: annual commitment required for best price; BBB complaints about refund processes
• Best for: women committed to a year-long GLP-1 program who want the lowest possible annual cost

Joi — $179 semaglutide, $249 tirzepatide, from a hormone-first clinic

Joi is the women's side of Joi + Blokes, a bioidentical-hormone telehealth company that added compounded GLP-1s rather than the other way round — the natural pick if you want one clinician looking at weight and perimenopause together. Semaglutide is $99 for the first month then $179, tirzepatide $149 then $249, with unlimited health coaching bundled and estradiol, progesterone and testosterone on the same account.

The catch is the contract: every plan is billed quarterly with a three-month minimum, the terms say all products are non-refundable, and some late-summer reviews quoted higher ongoing rates — confirm the price at checkout.

TrimRx — from $179 semaglutide, from $259 tirzepatide, locked through every dose

TrimRx's pitch is a price that never climbs with titration, and it delivers on that: whatever plan rate you enrol at holds through every dose, with consults, supplies and shipping included and a named 503A sterile pharmacy behind it. Approval is asynchronous and fast.

The headline rates only apply if you prepay a multi-month plan; month-to-month list runs about $299–$349 for semaglutide and ~$449 for tirzepatide, and unused prepaid months are not refunded once medication ships. A third of its Trustpilot reviews are one-star, almost all about auto-renewals and refund waits — read the billing terms twice.

Gala — $179 tirzepatide on a yearly plan, every dose included

Gala holds the lowest compounded tirzepatide rate on this page and it never climbs with your dose: $179 a month on a yearly plan, $199 a month on a 3-month plan, with the assessment, dose adjustments, messaging and shipping included. The platform is pitched at women in midlife specifically — estradiol, progesterone and non-hormonal hot-flash options sit on the same account from $69 a month — and prescribing runs through a licensed medical group in all 50 states.

Read the terms before you pay: the plans are prepaid and the refund policy returns nothing on cancellation. Gala never names its compounding pharmacy, so you cannot check its inspection history before enrolling, and its BBB file sits at C- with recurring billing complaints. The 3-month plan is the sensible way in.

ReadyRx — $199 semaglutide or $275 tirzepatide on a quarterly plan, flat at every dose

ReadyRx sells simplicity: one flat price at every dose, no membership fee, free cold-chain shipping and a written weight-loss guarantee for new patients who follow their prescribed doses. Semaglutide is $199 a month paid quarterly or $249 month-to-month; tirzepatide $275 quarterly or $315 monthly, each with $20 off the first month. Trustpilot sits at 4.7 across about 1,000 reviews.

The compounding pharmacy is not named before you enroll, care is text-only, and the service is not offered in about seven states for semaglutide (nine for tirzepatide, California and North Carolina among them) — the exclusions only surface during intake.

Curex — cheapest compounded tirzepatide without a prepaid plan

Curex offers compounded tirzepatide at roughly $199/mo all-in, with the consult and shipping in that figure and no membership or multi-month prepay — the closest rival to Gala for anyone who won't lock in a year. The price holds at the starter dose and should be confirmed before assuming it applies at higher titration levels.

NovoCare — cheapest brand-name entry point (Wegovy)

NovoCare's intro pricing is the most affordable way into brand-name Wegovy: $199/mo for the first two fills at starter doses (0.25mg–0.5mg). It rises to $349/mo at 0.5–1mg and $499/mo at 2mg, so the low rate only covers the first stretch of titration. It is the only FDA-approved semaglutide option in this comparison at an entry price this low.

• Pros: brand-name FDA-approved Wegovy; lowest intro price for brand-name semaglutide
• Cons: price rises significantly after the first two fills; not bundled with visits or coaching
• Best for: women who want brand-name Wegovy and are starting at a low, new-to-program dose

Henry Meds — oral or injectable compounded semaglutide, month-to-month

Henry Meds charges a single monthly price that includes everything: the compounded semaglutide (oral or injectable), clinician visits, lab review, and shipping. The oral version at $249/mo is the most affordable month-to-month oral compounded semaglutide here. Unlike some competitors, the price does not change as the dose escalates.

• Pros: clear all-in pricing; no membership fee stacked on top; no dose-escalation price hikes
• Cons: compounded product, not FDA-approved as a finished drug
• Best for: women who want the lowest consistent monthly cost for compounded semaglutide

Mochi Health — flat-price compounded tirzepatide across all doses

Mochi Health splits its cost into medication plus membership: $199 for the compounded 503A tirzepatide and roughly $79/mo for the membership, landing at about $278/mo all-in. The flat price holds across every dose, so titrating up never raises the bill — useful if you expect to reach higher maintenance levels.

• Pros: flat price across all doses; no dose-escalation hikes
• Cons: membership billed on top of the medication; compounded product, not FDA-approved as a finished drug
• Best for: women on compounded tirzepatide who want a single predictable price from starter to maintenance dose

Hims & Hers — brand-name Wegovy with a separate membership

Hims & Hers offers brand-name Wegovy starting around $149/mo for the oral form or $199/mo for the injectable, with a $149/mo membership billed separately on top — about $298–$348/mo all-in. As of March 2026 it no longer offers compounded semaglutide to new patients, so the brand-name route is the only option here — which makes the stacked membership a meaningful part of the real cost.

• Pros: brand-name FDA-approved Wegovy; oral and injectable both available
• Cons: $149/mo membership stacked on top; no compounded semaglutide for new patients as of March 2026
• Best for: women who specifically want brand-name Wegovy and value the Hims & Hers platform

LillyDirect — the only FDA-approved tirzepatide at this price tier

LillyDirect's self-pay Zepbound vials start at $299/mo for the 2.5mg dose, rising to $399/mo at 5mg and $449/mo at 7.5–15mg. It is more expensive than compounded tirzepatide, but the only FDA-approved option at this price range. Refills need to land within a 45-day window; miss it and prices jump to $499–$699.

• Pros: FDA-approved tirzepatide; no membership fee stacked on top
• Cons: pricier than compounded tirzepatide; refill window is tight
• Best for: women who want FDA-approved tirzepatide and don't need the lowest possible price

Annual cost comparison

At ongoing maintenance doses (after the intro period), the annual cost range looks like this: Henry Meds compounded semaglutide injection = ~$3,564/yr. Fridays compounded semaglutide (annual plan) = ~$1,800/yr. LillyDirect Zepbound 5mg = ~$4,788/yr. NovoCare ongoing (Wegovy, post-intro) = ~$4,188/yr. Henry Meds oral semaglutide = ~$2,988/yr. Among the newer flat-rate programs: JoinSkinny semaglutide = ~$1,937/yr (13 cycles of $149), LevelsRx from ~$1,800/yr, Joi semaglutide = ~$2,068/yr with the $99 first month, TrimRx semaglutide = ~$2,148/yr prepaid, Gala tirzepatide = ~$2,148/yr on the yearly plan, ReadyRx semaglutide = ~$2,388/yr quarterly. Brand-name at retail list (no savings program) = $16,000–$19,000+/yr.

Compounding legal status: what to know in 2026

FDA has been tightening enforcement around compounded GLP-1 medications since 2025. Semaglutide is no longer on the official drug shortage list, but 503A pharmacies can still legally compound it for individual patients under a prescriber's order. Tirzepatide similarly: broad 503B outsourcing facility compounding has faced restriction, but individual-patient 503A compounding continues.

This means your compounded GLP-1 prescription can still be filled legally, but the pathway is narrower than it was in 2023–2024 when shortage-based compounding was more broadly permitted. Ask your provider specifically which pharmacy model they use and whether they have contingency plans if regulatory conditions shift.