11 Compounded Semaglutide Providers (2026)

What compounded semaglutide actually is

Compounded semaglutide is semaglutide prepared by a licensed compounding pharmacy rather than manufactured as a commercial finished product. The active molecule is the same as Wegovy and Ozempic. The difference is the approval status: commercial semaglutide is FDA-approved as a finished drug (specific dose, formulation, manufacturer, tested for safety and efficacy). Compounded semaglutide is not FDA-approved as a finished product — it is prepared under a clinician's prescription for a specific patient.

This distinction matters. The FDA does not review compounded formulations for safety, efficacy, or quality the way it does commercial drugs. However, compounding pharmacies are regulated — 503A pharmacies must comply with state pharmacy laws and the federal DQSA; 503B outsourcing facilities have additional FDA oversight requirements.

Legal status in 2026: still available, but through a narrower pathway

Compounded semaglutide was made widely available by a 2022–2023 FDA drug shortage designation for the brand-name products. Pharmacies could compound semaglutide broadly during that shortage. When the FDA removed semaglutide from the shortage list in early 2024, most broad-scale compounding under the shortage provision ended.

What remains: 503A compounding pharmacies can still legally prepare compounded semaglutide for an individual patient when a prescriber determines there is a clinical need that the commercial drug cannot meet — for example, specific dosing requirements, documented allergies to excipients, or access and cost barriers. The FDA issued warning letters to non-compliant sellers in September 2025 and announced further enforcement steps in February 2026.

The practical implication: compounded semaglutide from a reputable 503A pharmacy, prescribed by a licensed telehealth provider for an individual patient, is still available and still legal. What has changed is that fly-by-night operations and non-compliant compounders have mostly exited or been warned. The providers listed here operate through 503A partnerships.

Compounded semaglutide provider breakdown

JoinSkinny — $149 per 28 days, flat at every dose

JoinSkinny has the lowest flat rate on this page: $149 per 28-day cycle for compounded semaglutide, and that number does not move as your clinician titrates you up. Prescribing runs through the OpenLoop medical groups and the terms name the partner pharmacies, so the supply chain is checkable, and the six-month weight-loss warranty is something almost no competitor puts in writing.

Two things to register before you enroll. Billing is every 28 days, not monthly — thirteen charges a year, so the real annual cost is closer to $1,937 than the $1,788 that "$149 × 12" suggests. And the warranty is narrow (standard doses only, BMI 30+ at the start, no missed weeks). It is also a young brand with a thin public review history, so keep your expectations of support modest.

LevelsRx — from $150, injection or oral, with video visits included

LevelsRx is the newest name here and the one that gives you a clinician on camera rather than a questionnaire: unlimited video visits, 1:1 nutrition coaching and shipping are bundled, and its partner pharmacies — including a known 503A compounder — are named in the terms. It also offers a daily oral liquid semaglutide at the same rate as the injection, which is rare at this price. The advertised "from $150 a month" is a floor: the actual plan tiers only appear once you begin the intake, the discounted rate reportedly carries a three-month minimum, and there are only a handful of public reviews to go on. Get the commitment terms in writing before you pay.

Fridays — cheapest on annual commitment

Fridays' annual plan at ~$150/mo is among the lowest prices for compounded semaglutide with clinical support included. At this price, the program bundles dietitian access, group coaching, and app features. The trade-off is the commitment: at the month-to-month rate ($249/mo), it is comparable to Henry Meds.

One note on Fridays' reviews: its Trustpilot rating is strong (4.4/5 on 4,000+ reviews) but the BBB profile shows a pattern of complaints about refund delays and shipping issues. Factor that in when deciding whether an annual prepayment makes sense for you.

Joi — $179 a month from a hormone-first clinic

Joi is the women's side of Joi + Blokes, a bioidentical-hormone telehealth company that added compounded GLP-1s rather than the other way round. That makes it the natural pick if you want one clinician looking at weight and perimenopause together: estradiol, progesterone and testosterone sit on the same account, and unlimited health coaching is bundled. Semaglutide runs $99 for the first month, then $179 a month.

The catch is the contract. Every plan is billed quarterly with a three-month minimum ($537 per block), the terms say all products are non-refundable, and some late-summer reviews quoted higher ongoing rates — confirm the $179 at checkout.

TrimRx — from $179, locked through every dose

TrimRx's pitch is a price that never climbs with titration, and it delivers on that: whatever plan rate you enrol at holds through every dose, with consults, supplies and shipping included and a named 503A sterile pharmacy behind it. Approval is asynchronous and fast, usually within a day or two.

The $179 headline only applies if you prepay twelve months; month-to-month list runs about $299–$349, and unused prepaid months are not refunded once medication ships. A third of its Trustpilot reviews are one-star, almost all about auto-renewals and refund waits — so read the billing terms twice before you commit.

ReadyRx — $199 quarterly or $249 monthly, flat at every dose

ReadyRx sells simplicity: one flat price at every semaglutide dose, no membership fee, free cold-chain shipping and a written weight-loss guarantee for new patients who follow their prescribed doses. Pay quarterly and it is $199 a month; pay month-to-month and it is $249, with $20 off the first month. Its Trustpilot score is 4.7 across about 1,000 reviews, and the company answers most of the negative ones.

The compounding pharmacy is not named before you enroll, care is text-only (no video or phone visit), and the service is not offered in about seven states, including Kentucky, Louisiana and South Carolina — the exclusions only surface during intake.

Peak Wellness — best rate if you commit annually

Peak Wellness rewards commitment: its annual-plan rate is about $229/mo, among the lowest here, while the month-to-month ongoing rate runs ~$349/mo. The flat rate holds across dose levels either way. As with Fridays, the cheap number assumes an annual prepayment — at the monthly rate it is the most expensive option on this page.

Henry Meds — oral or injectable, flat all-in, month-to-month

Henry Meds stands out because its pricing includes everything — the medication, clinician visits, supplies, and shipping — at a single monthly rate that does not increase with dose escalation. That last point matters: many programs charge more as the dose increases, which means the $199 starting price is not what you pay at month six. Henry Meds' flat-rate structure eliminates that surprise.

• Oral semaglutide: from $249/mo all-in
• Injectable semaglutide: from $297/mo all-in
• No membership, no titration surcharge
• 503A pharmacy, individual-patient prescription

Eden — lowest first-month entry

Eden has the gentlest on-ramp here: about $249 for the first month, then ~$329/mo ongoing. There is no membership fee and all doses are the same price, so the only thing that changes after month one is the step up to the standard rate. The low intro makes it cheap to try, but the ongoing $329 is at the higher end of this list — worth weighing if you expect to stay on it long-term.

Mochi Health — flat all-in price across doses

Mochi Health runs about $278/mo all-in: $199/mo for the compounded semaglutide injection plus a ~$79/mo membership. Like Henry Meds, the price is flat across dose levels, so titrating up does not raise your monthly cost. The membership fee is the structural difference — it sits on top of the medication rather than being bundled into a single number.

• Compounded semaglutide injection: $199/mo medication
• Membership: ~$79/mo
• All-in: ~$278/mo, flat across doses
• 503A pharmacy, individual-patient prescription

Ro — mostly brand-name now, compounded only in limited markets

Ro sits in this table as the brand-name reference point rather than a compounded option. Since 2025 it has focused on FDA-approved Wegovy, so if you go through Ro you are paying for the Wegovy pill at the NovoCare intro rate plus Ro's membership, not for a 503A preparation. That makes it the right comparison when you want to know what the brand costs next to the compounded programs above; its brand-name oral Wegovy runs roughly $149/mo on the NovoCare intro rate plus a ~$145/mo Ro membership. If compounded is your goal, the dedicated programs above are the surer bet.

Annual cost math: what a full year actually runs

At ongoing (non-intro) rates, a year of compounded semaglutide ranges roughly as follows: Henry Meds oral = ~$2,988/yr, injection = ~$3,564/yr. Fridays on the annual plan = ~$1,800/yr, versus ~$2,988/yr paying month-to-month. Mochi Health = ~$3,336/yr all-in. Eden's ongoing rate = ~$3,948/yr. Peak Wellness on its annual plan = ~$2,748/yr, versus ~$4,188/yr month-to-month. Among the newer flat-rate programs: JoinSkinny = ~$1,937/yr (13 cycles of $149), LevelsRx from ~$1,800/yr, Joi = ~$2,068/yr with the $99 first month, TrimRx = ~$2,148/yr on the prepaid year, and ReadyRx = ~$2,388/yr quarterly or ~$2,988/yr monthly. The pattern across every provider here: committing to an annual plan saves meaningfully over paying monthly, but locks you in if you need to stop or switch.

What compounded semaglutide does not include

Compounded semaglutide programs are cash-pay only — they cannot be billed to insurance. There is no manufacturer savings card (those programs apply only to brand-name Wegovy and Ozempic). No patient assistance programs exist for compounded versions. And because it is not FDA-approved, if something goes wrong with the formulation, there is no regulatory recourse available to the patient in the way there is for a commercial drug.

Who compounded semaglutide is and is not for

• Good fit: women who are not covered by insurance for weight-loss medications, have verified eligibility with their provider, and want supervised semaglutide at the lowest available cost
• Not ideal: women who want an FDA-approved product; women with insurance that covers brand-name Wegovy; women who would need ongoing prescription support if the provider exits the market
• Always ask: which 503A pharmacy compounds your medication, and what their quality control and testing protocols are