How much does semaglutide cost in 2026? Every pathway compared

Which semaglutide price applies to you?

• Insurance covers Wegovy: as little as $25 a month with Novo's savings card.
• On Medicare: $50 a month for Wegovy through the Medicare GLP-1 Bridge, if you meet its BMI rules.
• No coverage, want the FDA-approved drug: the Wegovy pill from about $150 a month, bought direct from Novo.
• No coverage, lowest monthly bill: compounded semaglutide from about $140 a month through Mochi Health.
• Can prepay a year: Fridays at about $150 a month, with a dietitian and coaching included.

Compounded semaglutide cost: about $140–$295 a month

Compounded semaglutide is mixed by a licensed pharmacy for each patient. It is not an FDA-approved finished product. It is the cheapest way to get semaglutide without insurance.

Through telehealth, it runs from about $140 to $295 a month without prepaying. Your price depends on the provider, your dose and how fees are billed.

Mochi Health: about $140–$270 a month, priced by dose

Mochi prices semaglutide by dose. The medicine costs $60 a month at the 0.22 mg starter dose. It rises to about $190 at the top 6.48 mg dose.

A separate $79 monthly membership covers your care. With it, the total runs about $140 to $270 a month. New members get their first month of membership free, so month one at the starter dose costs $60.

Paying the membership a year ahead lowers it to about $50 a month. Mochi now lets you compare partner pharmacies, so the medicine price can vary with the one you pick. Even at the top dose, Mochi's shot costs less each month than Fridays or the Henry Meds shot without prepaying. See our Mochi Health review.

Fridays: about $150–$280 a month, all-in

Fridays costs about $150 a month on a yearly plan paid upfront. Month to month, it costs about $280. That one price covers the medicine, provider visits, a dietitian and coaching.

A fall sale code lowers the yearly plan to about $115 a month. Prepaying carries risk. Fridays' terms say fees are not refunded if you cancel partway through a plan. Read our Fridays review before you commit.

Henry Meds: about $150–$295 a month, no membership

Henry Meds bundles visits, medicine, supplies and shipping into one monthly price. The shot costs about $295 month to month. It drops to about $245 a month on a 6-month prepay, and about $195 on a 12-month prepay.

The compounded tablet costs about $250 a month. Paid a year ahead, it comes to about $150 a month. The listed shot price covers doses up to about 1 mg a week, and Henry says prices vary with your plan and dose. See our Henry Meds review.

Brand Wegovy cost: list price, NovoCare and insurance

Wegovy's list price is about $1,350 a month. That is the maker's price before any discount. Almost no one needs to pay it. Novo Nordisk plans to cut it to about $675 on January 1, 2027.

With commercial insurance and the savings card: as little as $25 a month

If your work or private plan covers Wegovy, Novo's savings card can bring your cost down to $25 a month. The card pays at most $100 a month. So if your copay is above $125, you pay the difference.

The catch is coverage itself. You need the right plan and BMI. Plans often ask for prior authorization, which means they must approve the drug first. The card can't be used with Medicare or Medicaid.

On Medicare: $50 a month through the GLP-1 Bridge

Medicare members have their own route. From July 1, 2026 through December 31, 2027, the Medicare GLP-1 Bridge charges $50 a month for Wegovy. It covers any dose, pen or pill, for members who meet its BMI rules.

Without insurance: NovoCare self-pay from about $150 a month

Novo Nordisk sells both Wegovy forms direct. The pill starts at $149 a month at the 1.5 mg dose. It costs about $200 at 4 mg, and about $300 at the 9 and 25 mg doses.

New patients pay $199 a month for their first two pen fills, through December 31, 2026. After that, the pen costs about $350 a month. The 7.2 mg high-dose pen costs about $400.

This is FDA-approved Wegovy, not a compounded copy. GoodRx shows Novo's standard pen price at retail pharmacies, without the two $199 fills. Our Wegovy cost guide goes through each option in more detail.

Ozempic cost: a diabetes drug with its own pricing

Ozempic is FDA-approved for type 2 diabetes. Some doctors prescribe it off-label for weight loss, meaning outside its approved use. Insurance usually covers it only with a diabetes diagnosis.

Ozempic's list price is about $1,000 a month. At the pharmacy counter with no program, some stores charge more. Like Wegovy, its list price drops to about $675 on January 1, 2027.

Novo also sells Ozempic direct. New patients pay $199 a month for the first two pen fills. After that, the pen costs about $350 a month up to 1 mg, and about $500 at 2 mg.

Since May 4, 2026, the pill once sold as Rybelsus has been sold as the Ozempic pill. It starts at $149 a month and rises to about $300 at the highest dose. Like the pen, it is approved for type 2 diabetes. Our Ozempic cost guide has the full breakdown.

How Wegovy, Ozempic and compounded semaglutide differ

All three contain the same molecule, semaglutide. Wegovy is approved for weight management, as a weekly pen or a daily pill. Ozempic is approved for type 2 diabetes, also as a pen or a pill.

Compounded semaglutide is mixed by a pharmacy and is not FDA-approved. Each has its own price, access route and level of oversight.

The legal room for compounding has narrowed since the FDA declared the semaglutide shortage over in February 2025. A state-licensed pharmacy, called a 503A pharmacy, can still make it for one named patient with a documented medical need.

Large outsourcing facilities, called 503B, face tighter limits. In April 2026, the FDA proposed not adding semaglutide to the list of ingredients they may compound from. No final decision has been made. Ask any provider which pharmacy fills your prescription before you enroll. Our compounded semaglutide guide covers the rules in more depth.

Why semaglutide matters for women in perimenopause

Falling estrogen shifts fat toward the belly. It also makes it harder for your body to use insulin. Semaglutide doesn't change your hormones. It works by curbing appetite and slowing digestion.

In the STEP 1 trial, adults on weekly semaglutide lost about 15% of their body weight over 68 weeks. Those on placebo lost about 2%. Semaglutide does not treat hot flashes or other menopause symptoms.